Why XOCOVA
Get XOCOVA
Support
This website is intended for US audiences only.
You may have questions about XOCOVA. Explore our FAQs for the answers we’ve got for you.

COVID‑19=coronavirus disease 2019.
For medical inquiries, email medinfo@shionogi.com or call 1-800-849-9707.
For general product inquiries, call 1-877-4XOCOVA.
XOCOVA (ensitrelvir) is a prescription medicine used to help prevent coronavirus disease 2019 (COVID‑19) in adults and children aged 12 years and older following contact with a person who has COVID‑19 (post-exposure prophylaxis). It is not known if XOCOVA is safe and effective in children under age 12.
These are not the only medicines that may cause serious or life-threatening side effects if taken with XOCOVA. XOCOVA may increase or decrease the levels of many medicines in your body. Tell your healthcare provider (HCP) about all the medicines you take because additional laboratory tests or dose changes of your other medicines may be necessary during XOCOVA use. Your HCP may tell you about specific symptoms to watch for that may indicate you need to stop or decrease the dose of some of your other medicines.
Tell your HCP about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Your HCP can tell you if it is safe to take XOCOVA with other medicines. Do not start a new medicine without telling your HCP.
XOCOVA may cause serious side effects, including:
The most common side effects of XOCOVA include: headache, diarrhea, and cough.
These are not all possible side effects of XOCOVA. For more info, ask your HCP or pharmacist. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
Please see full Prescribing Information, including Patient Information, for XOCOVA.